| unscalable | (adjective) incapable of being ascended | Synonyms: unclimbable |
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| unscathed | (adjective) not injured or harmed | Synonyms: unharmed, unhurt, whole |
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| unscheduled | (adjective) not scheduled or not on a regular schedule | - |
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| unscholarly | (adjective) not scholarly | - |
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| unschooled | (adjective) lacking in schooling | Synonyms: untaught, untutored |
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| unscientific | (adjective) not consistent with the methods or principles of science | - |
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| unscientifically | (adverb) in an unscientific way; not according to the principles of science | - |
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| unscramble | (verb) make intelligible | - |
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| (verb) become or cause to become undone by separating the fibers or threads of | Synonyms: unknot, unpick, unravel, untangle |
| unscrew | (verb) loosen something by unscrewing it | - |
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| (verb) loosen by turning | - |
| unscripted | (adjective) not furnished with or using a script | - |
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| unscrupulous | (adjective) without scruples or principles | - |
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| unscrupulously | (adverb) without scruples | - |
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| unscrupulousness | (noun) the quality of unscrupulous dishonesty | - |
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