| unscalable | (adjective) incapable of being ascended | Synonyms: unclimbable |
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| unscathed | (adjective) not injured or harmed | Synonyms: unharmed, unhurt, whole |
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| unscheduled | (adjective) not scheduled or not on a regular schedule | - |
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| unscholarly | (adjective) not scholarly | - |
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| unschooled | (adjective) lacking in schooling | Synonyms: untaught, untutored |
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| unscientific | (adjective) not consistent with the methods or principles of science | - |
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| unscripted | (adjective) not furnished with or using a script | - |
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| unscrupulous | (adjective) without scruples or principles | - |
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