| upper | (adjective) the topmost one of two; upper | - |
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| (adjective) higher in place or position | - |
| (adjective) superior in rank or accomplishment | - |
| (noun) piece of leather or synthetic material that forms the part of a shoe or boot above the sole that encases the foot | - |
| (noun) a central nervous system stimulant that increases energy and decreases appetite; used to treat narcolepsy and some forms of depression | Synonyms: amphetamine, pep pill, speed |
| (noun) the higher of two berths | Synonyms: upper berth |
| uppercase | (adjective) relating to capital letters which were kept in the top half of a compositor's type case | - |
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| (noun) one of the large alphabetic characters used as the first letter in writing or printing proper names and sometimes for emphasis | Synonyms: capital, capital letter, majuscule, upper-case letter |
| uppercut | (noun) a swinging blow directed upward (especially at an opponent's chin) | - |
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| uppermost | (adjective) at or nearest to the top | Synonyms: topmost, upmost |
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| (adverb) in or into the highest position | - |
| (adverb) in or into the most prominent position, as in the mind | - |