| scab | (noun) the crustlike surface of a healing skin lesion | - |
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| (noun) someone who works (or provides workers) during a strike | Synonyms: blackleg, rat, strikebreaker |
| (verb) form a scab | - |
| (verb) take the place of work of someone on strike | Synonyms: blackleg, fink, rat |
| scabbard | (noun) a sheath for a sword or dagger or bayonet | - |
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| scabby | (adjective) covered with scabs | - |
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| scabicide | (noun) a drug that destroys the itch mite that causes scabies | - |
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| scabies | (noun) a contagious skin infection caused by the itch mite; characterized by persistent itching and skin irritation | Synonyms: itch |
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| scabiosa | (noun) any of various plants of the genus Scabiosa | Synonyms: scabious |
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| scabious | (noun) any of various plants of the genus Scabiosa | Synonyms: scabiosa |
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| scablands | (noun) (geology) flat elevated land with poor soil and little vegetation that is scarred by dry channels of glacial origin (especially in eastern Washington) | - |
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| scabrous | (adjective) dealing with salacious or indecent material | - |
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| (adjective) rough to the touch; covered with scales or scurf | Synonyms: lepidote, leprose, scaly, scurfy |