| opiate | (noun) a narcotic drug that contains opium or an opium derivative | - |
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| opine | (verb) expect, believe, or suppose | Synonyms: guess, imagine, reckon, suppose, think |
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| (verb) express one's opinion openly and without fear or hesitation | Synonyms: animadvert, sound off, speak out, speak up |
| opinion | (noun) the reason for a court's judgment (as opposed to the decision itself) | Synonyms: ruling |
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| (noun) a personal belief or judgment that is not founded on proof or certainty | Synonyms: persuasion, sentiment, thought, view |
| (noun) a belief or sentiment shared by most people; the voice of the people | Synonyms: popular opinion, public opinion, vox populi |
| (noun) a vague idea in which some confidence is placed | Synonyms: belief, feeling, impression, notion |
| (noun) the legal document stating the reasons for a judicial decision | Synonyms: judgement, judgment, legal opinion |
| (noun) a message expressing a belief about something; the expression of a belief that is held with confidence but not substantiated by positive knowledge or proof | Synonyms: view |
| opinionated | (adjective) obstinate in your opinions | Synonyms: opinionative, self-opinionated |
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| opinionative | (adjective) obstinate in your opinions | Synonyms: opinionated, self-opinionated |
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| opisthognathous | (adjective) having receding jaws | - |
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| opisthorchiasis | (noun) infestation with flukes obtained from eating raw fish; common in eastern Asia | - |
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| opisthotonos | (noun) severe spasm in which the back arches and the head bends back and heels flex toward the back | - |
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| opium | (noun) an addictive narcotic extracted from seed capsules of the opium poppy | - |
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