| deface | (verb) mar or spoil the appearance of | Synonyms: blemish, disfigure |
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| defalcate | (verb) appropriate (as property entrusted to one's care) fraudulently to one's own use | Synonyms: embezzle, malversate, misappropriate, peculate |
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| defame | (verb) charge falsely or with malicious intent; attack the good name and reputation of someone | Synonyms: asperse, besmirch, calumniate, denigrate, slander, smear, smirch, sully |
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| defang | (verb) remove the fangs from | - |
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| defat | (verb) remove the fat from | - |
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| default | (verb) fail to pay up | Synonyms: default on |
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| defeat | (verb) win a victory over | Synonyms: get the better of, overcome |
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| (verb) thwart the passage of | Synonyms: kill, shoot down, vote down, vote out |
| defecate | (verb) have a bowel movement | Synonyms: ca-ca, crap, make, shit, stool, take a crap, take a shit |
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| defect | (verb) desert (a cause, a country or an army), often in order to join the opposing cause, country, or army | Synonyms: desert |
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| defeminise | (verb) remove the ovaries of (female mammals such as cats) | Synonyms: defeminize |
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| defeminize | (verb) remove the ovaries of (female mammals such as cats) | Synonyms: defeminise |
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| defend | (verb) argue or speak in defense of | Synonyms: fend for, support |
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| (verb) state or assert | Synonyms: maintain |
| (verb) be on the defensive; act against an attack | - |
| (verb) protect against a challenge or attack | Synonyms: guard, hold |
| (verb) protect or fight for as a champion | Synonyms: champion |
| (verb) fight against or resist strongly | Synonyms: fight, fight back, fight down, oppose |
| (verb) be the defense counsel for someone in a trial | Synonyms: represent |
| defenestrate | (verb) throw through or out of the window | - |
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| defer | (verb) yield to another's wish or opinion | Synonyms: accede, bow, give in, submit |
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| (verb) hold back to a later time | Synonyms: hold over, postpone, prorogue, put off, put over, remit, set back, shelve, table |
| defervesce | (verb) experience an abatement of a fever | - |
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| defibrillate | (verb) stop the fibrillation and restore normal contractions, usually by means of electric shocks | - |
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| defibrinate | (verb) remove fibrin from (blood) | - |
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| defile | (verb) spot, stain, or pollute | Synonyms: befoul, foul, maculate |
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| (verb) make dirty or spotty, as by exposure to air; also used metaphorically | Synonyms: maculate, stain, sully, tarnish |
| (verb) place under suspicion or cast doubt upon | Synonyms: cloud, corrupt, sully, taint |
| define | (verb) give a definition for the meaning of a word | - |
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| (verb) decide upon or fix definitely | Synonyms: determine, fix, limit, set, specify |
| (verb) determine the essential quality of | Synonyms: delimit, delimitate, delineate, specify |
| (verb) determine the nature of | - |
| (verb) show the form or outline of | Synonyms: delineate |
| deflagrate | (verb) burn with great heat and intense light | - |
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| (verb) cause to burn rapidly and with great intensity | - |
| deflate | (verb) become deflated or flaccid, as by losing air | - |
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| (verb) reduce or cut back the amount or availability of, creating a decline in value or prices | - |
| (verb) produce deflation in | - |
| (verb) reduce or lessen the size or importance of | Synonyms: puncture |
| (verb) release contained air or gas from | - |
| (verb) collapse by releasing contained air or gas | - |
| deflect | (verb) impede the movement of (an opponent or a ball) | Synonyms: block, parry |
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| (verb) draw someone's attention away from something | Synonyms: distract |
| (verb) turn aside and away from an initial or intended course | - |
| (verb) turn from a straight course, fixed direction, or line of interest | Synonyms: bend, turn away |
| (verb) prevent the occurrence of; prevent from happening; to protect from or to keep away anything undesirable; to ward off | Synonyms: avert, avoid, debar, fend off, forefend, forfend, head off, obviate, stave off, ward off |
| deflower | (verb) make imperfect | Synonyms: impair, mar, spoil, vitiate |
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| (verb) deprive of virginity | Synonyms: ruin |
| defog | (verb) free from mist | Synonyms: demist |
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| defoliate | (verb) strip the leaves or branches from | - |
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| deforest | (verb) remove the trees from | Synonyms: disafforest, disforest |
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| deform | (verb) become misshapen | - |
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| (verb) alter the shape of (something) by stress | Synonyms: distort, strain |
| (verb) assume a different shape or form | Synonyms: change form, change shape |
| (verb) make formless | - |
| (verb) cause (an object) to assume a crooked or angular form | Synonyms: bend, flex, turn, twist |
| (verb) twist and press out of shape | Synonyms: contort, distort, wring |
| defraud | (verb) deprive of by deceit | Synonyms: bunco, con, diddle, goldbrick, hornswoggle, mulct, nobble, rook, scam, short-change, swindle, victimize |
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| defray | (verb) bear the expenses of | - |
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| defrock | (verb) divest of the frock; of church officials | Synonyms: unfrock |
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| defrost | (verb) make or become free of frost or ice | Synonyms: de-ice, deice |
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| defuse | (verb) remove the triggering device from | - |
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| defy | (verb) challenge | Synonyms: dare |
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| (verb) resist or confront with resistance | Synonyms: hold, hold up, withstand |
| (verb) elude, especially in a baffling way | Synonyms: refuse, resist |