| spik | (noun) (ethnic slur) offensive term for persons of Latin American descent | Synonyms: spic, spick |
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| spike | (noun) sports equipment consisting of a sharp point on the sole of a shoe worn by athletes | - |
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| (noun) a large stout nail | - |
| (noun) any holding device consisting of a rigid, sharp-pointed object | Synonyms: spindle |
| (noun) a long, thin sharp-pointed implement (wood or metal) | - |
| (noun) a sharp-pointed projection along the top of a fence or wall (or a dinosaur) | - |
| (noun) a very high narrow heel on women's shoes | Synonyms: spike heel, stiletto heel |
| (noun) each of the sharp points on the soles of athletic shoes to prevent slipping (or the shoes themselves) | - |
| (noun) a transient variation in voltage or current | - |
| (noun) a sharp rise followed by a sharp decline | - |
| (noun) (botany) an indeterminate inflorescence bearing sessile flowers on an unbranched axis | - |
| (noun) fruiting spike of a cereal plant especially corn | Synonyms: capitulum, ear |
| spikelet | (noun) a small sharp-pointed tip resembling a spike on a stem or leaf | Synonyms: pricker, prickle, spine, sticker, thorn |
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| spikemoss | (noun) any of numerous fern allies of the genus Selaginella | Synonyms: little club moss, spike moss |
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| spikenard | (noun) an aromatic ointment used in antiquity | Synonyms: nard |
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