| skunk | (noun) American musteline mammal typically ejecting an intensely malodorous fluid when startled; in some classifications put in a separate subfamily Mephitinae | Synonyms: polecat, wood pussy |
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| (noun) street names for marijuana | Synonyms: dope, gage, grass, green goddess, locoweed, Mary Jane, pot, sens, sess, smoke, weed |
| (noun) a defeat in a game where one side fails to score | Synonyms: shutout |
| (noun) a person who is deemed to be despicable or contemptible | Synonyms: bum, crumb, dirty dog, git, lowlife, puke, rat, rotter, scum bag, scumbag, so-and-so, stinker, stinkpot |
| skunkbush | (noun) deciduous shrub of California with unpleasantly scented usually trifoliate leaves and edible fruit | Synonyms: Rhus trilobata, squaw-bush, squawbush |
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| skunkweed | (noun) tall herb of the Rocky Mountains having sticky leaves and an offensive smell | Synonyms: Polemonium viscosum, skunk-weed |
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