| melaena | (noun) abnormally dark tarry feces containing blood (usually from gastrointestinal bleeding) | Synonyms: melena |
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| melagra | (noun) rheumatic or myalgic pains in the arms or legs | - |
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| melamine | (noun) a white crystalline organic base; used mainly in making melamine resins | Synonyms: cyanuramide |
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| melancholia | (noun) extreme depression characterized by tearful sadness and irrational fears | - |
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| melancholiac | (noun) someone subject to melancholia | Synonyms: melancholic |
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| melancholic | (noun) someone subject to melancholia | Synonyms: melancholiac |
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| melancholy | (noun) a humor that was once believed to be secreted by the kidneys or spleen and to cause sadness and melancholy | Synonyms: black bile |
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| (noun) a feeling of thoughtful sadness | - |
| (noun) a constitutional tendency to be gloomy and depressed | - |
| melange | (noun) a motley assortment of things | Synonyms: farrago, gallimaufry, hodgepodge, hotchpotch, mingle-mangle, mishmash, oddments, odds and ends, omnium-gatherum, ragbag |
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| melanin | (noun) insoluble pigments that account for the color of e.g. skin and scales and feathers | - |
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| melanism | (noun) a condition characterized by abnormal deposits of melanin (especially in the skin) | Synonyms: melanosis |
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| melanoblast | (noun) an epidermal cell that is a precursor of a melanocyte | - |
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| melanocyte | (noun) a cell in the basal layer of the epidermis that produces melanin under the control of the melanocyte-stimulating hormone | - |
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| melanoderma | (noun) abnormally dark skin caused by increased deposits of melatonin | - |
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| melanoma | (noun) any of several malignant neoplasms (usually of the skin) consisting of melanocytes | Synonyms: malignant melanoma |
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| melanosis | (noun) a condition characterized by abnormal deposits of melanin (especially in the skin) | Synonyms: melanism |
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| melasma | (noun) a tan discoloration of a woman's face that is associated with pregnancy or with the use of oral contraceptives | Synonyms: chloasma, mask of pregnancy |
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| melatonin | (noun) hormone secreted by the pineal gland | - |
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| meld | (noun) a form of rummy using two decks of cards and four jokers; jokers and deuces are wild; the object is to form groups of the same rank | Synonyms: basket rummy, canasta |
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| melee | (noun) a noisy riotous fight | Synonyms: battle royal, scrimmage |
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| melena | (noun) abnormally dark tarry feces containing blood (usually from gastrointestinal bleeding) | Synonyms: melaena |
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| melilot | (noun) erect annual or biennial plant grown extensively especially for hay and soil improvement | Synonyms: melilotus, sweet clover |
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| melilotus | (noun) erect annual or biennial plant grown extensively especially for hay and soil improvement | Synonyms: melilot, sweet clover |
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| melioration | (noun) the act of relieving ills and changing for the better | Synonyms: amelioration, betterment |
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| (noun) the linguistic process in which over a period of time a word grows more positive in connotation or more elevated in meaning | - |
| (noun) a condition superior to an earlier condition | Synonyms: improvement |
| meliorism | (noun) the belief that the world can be made better by human effort | - |
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| meliorist | (noun) a disputant who advocates reform | Synonyms: crusader, reformer, reformist, social reformer |
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| mellitate | (noun) a salt of mellitic acid. | - |
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| mellowing | (noun) the process of becoming mellow | - |
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| mellowness | (noun) the property of a sensation that is rich and pleasing | Synonyms: fullness, richness |
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| (noun) a soft shade of a color | - |
| (noun) geniality, as through the effects of alcohol or marijuana | - |
| (noun) a taste (especially of fruit) that is ripe and of full flavor | - |
| (noun) a feeling of good humor and sympathy through maturity or intoxication or a relaxed state | - |
| melodiousness | (noun) the property of having a melody | Synonyms: tunefulness |
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| melodrama | (noun) an extravagant comedy in which action is more salient than characterization | - |
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| melody | (noun) the perception of pleasant arrangements of musical notes | Synonyms: tonal pattern |
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| (noun) a succession of notes forming a distinctive sequence | Synonyms: air, line, melodic line, melodic phrase, strain, tune |
| meloid | (noun) beetle that produces a secretion that blisters the skin | Synonyms: blister beetle |
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| melon | (noun) any of numerous fruits of the gourd family having a hard rind and sweet juicy flesh | - |
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| (noun) any of various fruit of cucurbitaceous vines including: muskmelons, watermelons, cantaloupes, cucumbers | Synonyms: melon vine |
| melosa | (noun) South American herb with sticky glandular foliage; source of madia oil | Synonyms: Chile tarweed, madia oil plant, Madia sativa |
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| melphalan | (noun) antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies | Synonyms: Alkeran |
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| melt | (noun) the process whereby heat changes something from a solid to a liquid | Synonyms: melting, thaw, thawing |
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| meltability | (noun) Capability of being reduced from a solid to a liquid state usually by heat. | - |
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| meltdown | (noun) a disaster comparable to a nuclear meltdown | - |
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| (noun) severe overheating of the core of a nuclear reactor resulting in the core melting and radiation escaping | Synonyms: nuclear meltdown |
| melter | (noun) a worker who melts substances (metal or wax etc.) | - |
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| melting | (noun) the process whereby heat changes something from a solid to a liquid | Synonyms: melt, thaw, thawing |
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| meltwater | (noun) melted snow or ice | - |
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