| despair | (noun) the feeling that everything is wrong and nothing will turn out well | - |
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| (noun) a state in which all hope is lost or absent | Synonyms: desperation |
| despatch | (noun) the act of sending off something | Synonyms: dispatch, shipment |
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| (noun) killing a person or animal | Synonyms: dispatch |
| (noun) the property of being prompt and efficient | Synonyms: dispatch, expedition, expeditiousness |
| (noun) an official report (usually sent in haste) | Synonyms: communique, dispatch |
| desperado | (noun) a bold outlaw (especially on the American frontier) | Synonyms: desperate criminal |
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| desperate | (noun) a person who is frightened and in need of help | - |
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| desperation | (noun) desperate recklessness | - |
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| (noun) a state in which all hope is lost or absent | Synonyms: despair |
| despicability | (noun) unworthiness by virtue of lacking higher values | Synonyms: baseness, contemptibility, despicableness, sordidness |
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| despicableness | (noun) unworthiness by virtue of lacking higher values | Synonyms: baseness, contemptibility, despicability, sordidness |
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| despisal | (noun) a feeling of scornful hatred | Synonyms: despising |
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| despising | (noun) a feeling of scornful hatred | Synonyms: despisal |
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| despite | (noun) contemptuous disregard | - |
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| (noun) lack of respect accompanied by a feeling of intense dislike | Synonyms: contempt, disdain, scorn |
| despoilation | (noun) the act of stripping and taking by force | Synonyms: despoilment, despoliation, spoil, spoilation, spoliation |
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| despoiler | (noun) someone who takes spoils or plunder (as in war) | Synonyms: freebooter, looter, pillager, plunderer, raider, spoiler |
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| despoilment | (noun) the act of stripping and taking by force | Synonyms: despoilation, despoliation, spoil, spoilation, spoliation |
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| despoliation | (noun) the act of stripping and taking by force | Synonyms: despoilation, despoilment, spoil, spoilation, spoliation |
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| despondence | (noun) feeling downcast and disheartened and hopeless | Synonyms: despondency, disconsolateness, heartsickness |
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| despondency | (noun) feeling downcast and disheartened and hopeless | Synonyms: despondence, disconsolateness, heartsickness |
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| despot | (noun) a cruel and oppressive dictator | Synonyms: autocrat, tyrant |
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| despotism | (noun) a form of government in which the ruler is an absolute dictator (not restricted by a constitution or laws or opposition etc.) | Synonyms: absolutism, authoritarianism, Caesarism, dictatorship, monocracy, one-man rule, shogunate, Stalinism, totalitarianism, tyranny |
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| (noun) dominance through threat of punishment and violence | Synonyms: absolutism, tyranny |