| sodom | (noun) any location known for vice and corruption | - |
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| som | (noun) the basic unit of money in Kyrgyzstan | - |
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| (noun) the basic unit of money in Uzbekistan | - |
| stardom | (noun) the status of being acknowledged as a star | - |
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| stateroom | (noun) a guest cabin | - |
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| stillroom | (noun) a pantry or storeroom connected with the kitchen (especially in a large house) for preparing tea and beverages and for storing liquors and preserves and tea etc | Synonyms: still room |
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| stockroom | (noun) storeroom for storing goods and supplies used in a business | Synonyms: stock room |
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| storeroom | (noun) a room in which things are stored | Synonyms: storage room, stowage |
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| strongroom | (noun) a burglarproof and fireproof room in which valuables are kept | - |
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| subkingdom | (noun) (biology) a taxonomic group comprising a major division of a kingdom | - |
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| sunroom | (noun) a room enclosed largely with glass and affording exposure to the sun | Synonyms: solarium, sun lounge, sun parlor, sun parlour, sun porch, sunporch |
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| supermom | (noun) an informal term for a mother who can combine childcare and full-time employment | - |
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| symptom | (noun) anything that accompanies X and is regarded as an indication of X's existence | - |
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| (noun) (medicine) any sensation or change in bodily function that is experienced by a patient and is associated with a particular disease | - |
| taproom | (noun) a room or establishment where alcoholic drinks are served over a counter | Synonyms: bar, barroom, ginmill, saloon |
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| tearoom | (noun) a restaurant where tea and light meals are available | Synonyms: tea parlor, tea parlour, teahouse, teashop |
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| telecom | (noun) (often plural) systems used in transmitting messages over a distance electronically | Synonyms: telecommunication |
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| thraldom | (noun) the state of being under the control of another person | Synonyms: bondage, slavery, thrall, thralldom |
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| thralldom | (noun) the state of being under the control of another person | Synonyms: bondage, slavery, thraldom, thrall |
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| tom | (noun) male cat | Synonyms: tomcat |
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| (noun) male turkey | Synonyms: gobbler, tom turkey, turkey cock |
| transom | (noun) a horizontal crosspiece across a window or separating a door from a window over it | Synonyms: traverse |
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| (noun) a window above a door that is usually hinged to a horizontal crosspiece over the door | Synonyms: fanlight, transom window |
| venom | (noun) feeling a need to see others suffer | Synonyms: malice, maliciousness, spite, spitefulness |
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| (noun) toxin secreted by animals; secreted by certain snakes and poisonous insects (e.g., spiders and scorpions) | - |
| vroom | (noun) the roaring sound made by a motor that is running at high speed | - |
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| wardroom | (noun) military quarters for dining and recreation for officers of a warship (except the captain) | - |
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| washroom | (noun) a lavatory (particularly a lavatory in a public place) | - |
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| whoredom | (noun) offering sexual intercourse for pay | Synonyms: harlotry, prostitution |
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| wisdom | (noun) the trait of utilizing knowledge and experience with common sense and insight | Synonyms: wiseness |
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| (noun) the quality of being prudent and sensible | Synonyms: soundness, wiseness |
| (noun) ability to apply knowledge or experience or understanding or common sense and insight | Synonyms: sapience |
| (noun) accumulated knowledge or erudition or enlightenment | - |
| workroom | (noun) room where work is done | - |
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| zoom | (noun) the act of rising upward into the air | Synonyms: soar |
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| (noun) a rapid rise | Synonyms: rapid climb, rapid growth |