| anaspid | (noun) extinct small freshwater jawless fish usually having a heterocercal tail and an armored head; of the Silurian and Devonian | - |
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| aspidistra | (noun) evergreen perennial with large handsome basal leaves; grown primarily as a foliage houseplant | Synonyms: Aspidistra elatio, bar-room plant, cast-iron plant |
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| bicuspid | (noun) a tooth having two cusps or points; located between the incisors and the molars | Synonyms: premolar |
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| cephalaspid | (noun) extinct jawless fish of the Devonian with armored head | Synonyms: osteostracan |
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| cuspid | (noun) one of the four pointed conical teeth (two in each jaw) located between the incisors and the premolars | Synonyms: canine, canine tooth, dogtooth, eye tooth, eyetooth |
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| cuspidation | (noun) a decoration using cusps | - |
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| cuspidor | (noun) a receptacle for spit (usually in a public place) | Synonyms: spittoon |
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| mantispid | (noun) insect that resembles a mantis; larvae are parasites in the nests of spiders and wasps | - |
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| spider | (noun) predatory arachnid with eight legs, two poison fangs, two feelers, and usually two silk-spinning organs at the back end of the body; they spin silk to make cocoons for eggs or traps for prey | - |
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| (noun) a skillet made of cast iron | - |
| (noun) a computer program that prowls the internet looking for publicly accessible resources that can be added to a database; the database can then be searched with a search engine | Synonyms: wanderer |
| spiderflower | (noun) any of various often strong-smelling plants of the genus Cleome having showy spider-shaped flowers | Synonyms: cleome |
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| spiderwort | (noun) any plant of the family Commelinaceae | Synonyms: dayflower |
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| vespid | (noun) mostly social nest-building wasps | Synonyms: vespid wasp |
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