| spaceward | (adverb) towards outer space | Synonyms: spacewards |
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| spacewards | (adverb) towards outer space | Synonyms: spaceward |
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| spaciously | (adverb) with ample room | Synonyms: roomily |
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| sparingly | (adverb) to a meager degree or in a meager manner | Synonyms: meagerly, meagrely, slenderly |
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| sparsely | (adverb) in a sparse way | - |
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| spasmodically | (adverb) in spurts and fits | - |
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| (adverb) with spasms | Synonyms: jerkily |
| spatially | (adverb) with regard to space | - |
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| specially | (adverb) to a distinctly greater extent or degree than is common | Synonyms: especially, particularly, peculiarly |
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| (adverb) in a special manner | Synonyms: especially |
| specifically | (adverb) in distinction from others | - |
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| speciously | (adverb) in a specious manner | - |
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| spectacularly | (adverb) in a spectacular manner | Synonyms: stunningly |
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| spectrographically | (adverb) by spectrographic means | - |
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| speculatively | (adverb) with speculation; in a speculative manner | - |
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| speechlessly | (adverb) in a manner indicating that one is deprived of speech by physical weakness or emotion | - |
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| speedily | (adverb) with speed | Synonyms: apace, chop-chop, in short order, quickly, rapidly |
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| spherically | (adverb) in a spherical manner | - |
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| spicily | (adverb) with strong spices; in a spicy manner | Synonyms: piquantly |
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| spinally | (adverb) in the spine | - |
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| spirally | (adverb) with spirals | - |
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| spiritedly | (adverb) in a spirited or lively manner; with animation and vivacity | - |
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| spiritually | (adverb) in a spiritual manner | - |
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| spitefully | (adverb) with spite; in a spiteful manner | - |
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| (adverb) in a maliciously spiteful manner | Synonyms: despitefully |
| splendidly | (adverb) wonderfully | Synonyms: excellently, famously, magnificently |
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| (adverb) in an impressively beautiful manner | Synonyms: gorgeously, magnificently, resplendently |
| spontaneously | (adverb) in a spontaneous manner | - |
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| (adverb) without advance preparation | Synonyms: ad lib, ad libitum, impromptu |
| spookily | (adverb) in an unnatural eery manner | Synonyms: eerily |
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| sporadically | (adverb) in a sporadic manner | Synonyms: periodically |
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| sportingly | (adverb) so as to be sporting; in a sporting manner | - |
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| sportively | (adverb) in a merry sportive manner | - |
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| spotlessly | (adverb) in a spotless manner | - |
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| sprucely | (adverb) in a fashionable manner | Synonyms: modishly, smartly |
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| spuriously | (adverb) in a false and spurious manner | - |
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