| sic | (adverb) intentionally so written (used after a printed word or phrase) | - |
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| sickeningly | (adverb) in a disgusting manner or to a disgusting degree | Synonyms: disgustingly, distastefully, revoltingly |
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| sidearm | (adverb) in a sidearm manner | - |
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| sidelong | (adverb) to, toward or at one side | Synonyms: obliquely, sideways |
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| (adverb) with the side toward someone or something | - |
| (adverb) on the side | - |
| sidesaddle | (adverb) on or as if on a sidesaddle | - |
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| sidesplittingly | (adverb) in a very humorous manner | Synonyms: killingly |
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| sideward | (adverb) toward one side | Synonyms: sidewards |
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| sidewards | (adverb) toward one side | Synonyms: sideward |
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| sideway | (adverb) from the side; obliquely | Synonyms: sideways, sidewise |
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| (adverb) with one side forward or to the front | Synonyms: sideways, sidewise |
| (adverb) in a lateral direction | Synonyms: sideways, sidewise |
| sideways | (adverb) to, toward or at one side | Synonyms: obliquely, sidelong |
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| (adverb) from the side; obliquely | Synonyms: sideway, sidewise |
| (adverb) with one side forward or to the front | Synonyms: sideway, sidewise |
| (adverb) in a lateral direction | Synonyms: sideway, sidewise |
| sidewise | (adverb) from the side; obliquely | Synonyms: sideway, sideways |
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| (adverb) with one side forward or to the front | Synonyms: sideway, sideways |
| (adverb) in a lateral direction | Synonyms: sideway, sideways |
| signally | (adverb) in a signal manner | Synonyms: remarkably, unmistakably |
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| (adverb) as a signal | - |
| significantly | (adverb) in an important way or to an important degree | Synonyms: importantly |
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| (adverb) in a significant manner | - |
| (adverb) in a statistically significant way | - |
| silently | (adverb) without speaking | Synonyms: mutely, taciturnly, wordlessly |
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| silkily | (adverb) in a silky manner | - |
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| similarly | (adverb) in like or similar manner | Synonyms: likewise |
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| simperingly | (adverb) with a lack of courage and determination | Synonyms: pusillanimously |
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| simply | (adverb) and nothing more | Synonyms: but, just, merely, only |
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| (adverb) in a simple manner; without extravagance or embellishment | Synonyms: plainly |
| (adverb) absolutely; altogether; really | - |
| (adverb) (used for emphasis) absolutely | Synonyms: just |
| simultaneously | (adverb) at the same instant | Synonyms: at the same time |
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| sincerely | (adverb) with sincerity; without pretense | Synonyms: truly, unfeignedly |
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| (adverb) written formula for ending a letter | Synonyms: sincerely yours |
| singly | (adverb) one by one; one at a time | - |
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| (adverb) apart from others | Synonyms: individually, on an individual basis, one by one, separately, severally |
| singularly | (adverb) in a singular manner or to a singular degree | - |
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| sinuously | (adverb) in a sinuous manner | - |
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| sinusoidally | (adverb) in a sinusoidal manner | - |
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| sixfold | (adverb) by a factor of six | Synonyms: six times |
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| sixthly | (adverb) in the sixth place | - |
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