| searchingly | (adverb) in a searching manner | - |
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| seasonably | (adverb) at an opportune time | Synonyms: apropos, timely, well-timed |
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| (adverb) in accordance with the season | - |
| seasonally | (adverb) depending on the season | - |
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| seaward | (adverb) in the direction of the sea | Synonyms: asea, seawards |
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| seawards | (adverb) in the direction of the sea | Synonyms: asea, seaward |
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| second | (adverb) in the second place | Synonyms: secondly |
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| secondarily | (adverb) of secondary import | - |
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| secondhand | (adverb) by indirect means | - |
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| secondly | (adverb) in the second place | Synonyms: second |
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| secretively | (adverb) in a secretive manner; with a preference for secrecy | - |
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| secretly | (adverb) in secrecy; not openly | Synonyms: in secret, on the Q.T., on the QT |
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| (adverb) not openly; inwardly | - |
| securely | (adverb) in a secure manner; in a manner free from danger | Synonyms: firmly |
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| (adverb) in an invulnerable manner | - |
| (adverb) in a manner free from fear or risk | - |
| (adverb) in a confident and unselfconscious manner | - |
| sedately | (adverb) in a sedate manner | Synonyms: calmly |
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| seductively | (adverb) in a tempting seductive manner | Synonyms: temptingly |
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| sedulously | (adverb) in a sedulous manner | - |
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| seemingly | (adverb) from appearances alone | Synonyms: apparently, on the face of it, ostensibly |
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| seldom | (adverb) not often | Synonyms: rarely |
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| selectively | (adverb) by selection; in a selective manner | - |
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| selfishly | (adverb) in an egotistical manner | Synonyms: egotistically |
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| selflessly | (adverb) in an altruistic manner | Synonyms: altruistically |
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| semantically | (adverb) with regard to meaning | - |
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| semiannually | (adverb) twice a year | Synonyms: biyearly |
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| semimonthly | (adverb) twice a month | Synonyms: bimonthly |
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| semiweekly | (adverb) twice a week | Synonyms: biweekly |
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| sensationally | (adverb) in a sensational manner | - |
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| senselessly | (adverb) in an unreasonably senseless manner | Synonyms: mindlessly |
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| (adverb) in a meaningless and purposeless manner | - |
| sensibly | (adverb) with good sense or in a reasonable or intelligent manner | Synonyms: reasonably, sanely |
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| sensitively | (adverb) in a sensitive manner | - |
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| sensually | (adverb) in a sultry and sensual manner | Synonyms: sultrily |
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| sensuously | (adverb) with aesthetic gratification or delight | - |
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| sententiously | (adverb) in a pithy sententious manner | Synonyms: pithily |
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| sentimentally | (adverb) in a sentimental manner | - |
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| separably | (adverb) with possibility of separation or individuation | - |
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| separately | (adverb) apart from others | Synonyms: individually, on an individual basis, one by one, severally, singly |
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| sequentially | (adverb) in a sequential manner | Synonyms: consecutive |
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| serenely | (adverb) in a peacefully serene manner | - |
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| serially | (adverb) in a serial manner | - |
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| seriatim | (adverb) in a series; point by point | - |
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| seriously | (adverb) in a serious manner | Synonyms: earnestly, in earnest |
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| (adverb) to a severe or serious degree | Synonyms: badly, gravely, severely |
| servilely | (adverb) in an obsequious manner | Synonyms: obsequiously, subserviently |
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| sevenfold | (adverb) seven times | - |
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| seventhly | (adverb) in the seventh place | - |
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| severally | (adverb) apart from others | Synonyms: individually, on an individual basis, one by one, separately, singly |
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| (adverb) individually or separately | Synonyms: independently |
| (adverb) in the order given | Synonyms: respectively |
| severely | (adverb) to a severe or serious degree | Synonyms: badly, gravely, seriously |
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| (adverb) with sternness; in a severe manner | Synonyms: sternly |
| (adverb) causing great damage or hardship | Synonyms: hard |
| sexually | (adverb) by sexual means | - |
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| (adverb) with respect to sexuality | - |