| irately | (adverb) in an irate manner | - |
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| ironically | (adverb) in an ironic manner | - |
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| (adverb) contrary to plan or expectation | - |
| irrationally | (adverb) in an irrational manner | - |
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| irregardless | (adverb) regardless; a combination of irrespective and regardless sometimes used humorously | - |
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| irregularly | (adverb) in an inconstant manner, not according to fixed rate or schedule | Synonyms: on an irregular basis |
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| (adverb) at an uneven rate | - |
| (adverb) having an irregular form | - |
| irrelevantly | (adverb) in an irrelevant manner | - |
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| irreparably | (adverb) in an irreparable manner or to an irreparable degree | - |
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| irreproachably | (adverb) in an irreproachable and blameless manner | Synonyms: blamelessly |
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| irresistibly | (adverb) incapable of being resisted | Synonyms: overpoweringly, overwhelmingly |
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| irresolutely | (adverb) lacking determination or decisiveness | - |
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| irrespective | (adverb) in spite of everything; without regard to drawbacks | Synonyms: disregarding, disregardless, no matter, regardless |
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| irresponsibly | (adverb) in an irresponsible manner | - |
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| irretrievably | (adverb) in an irretrievable manner | - |
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| irreverently | (adverb) without respect | - |
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| (adverb) in an irreverent manner | - |
| irreversibly | (adverb) in an irreversible manner | - |
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| irrevocably | (adverb) in an irrevocable manner | - |
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| irritably | (adverb) in an irritable manner | - |
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| (adverb) in a petulant manner | Synonyms: pettishly, petulantly, testily |
| irritatingly | (adverb) in an irritating manner | - |
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