| opponent | (adjective) characterized by active hostility | Synonyms: opposing |
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| opportune | (adjective) suitable or at a time that is suitable or advantageous especially for a particular purpose | - |
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| opportunist | (adjective) taking immediate advantage, often unethically, of any circumstance of possible benefit | Synonyms: opportunistic, timeserving |
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| opportunistic | (adjective) taking immediate advantage, often unethically, of any circumstance of possible benefit | Synonyms: opportunist, timeserving |
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| opposable | (adjective) capable of being placed opposite to something | Synonyms: apposable |
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| opposed | (adjective) being in opposition or having an opponent | - |
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| opposing | (adjective) characterized by active hostility | Synonyms: opponent |
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| opposite | (adjective) of leaves etc; growing in pairs on either side of a stem | Synonyms: paired |
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| (adjective) characterized by opposite extremes; completely opposed | Synonyms: diametric, diametrical, polar |
| (adjective) the other one of a complementary pair | - |
| (adjective) being directly across from each other; facing | - |
| (adjective) altogether different in nature or quality or significance | - |
| (adjective) moving or facing away from each other | - |
| oppositive | (adjective) expressing antithesis or opposition | Synonyms: adversative |
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| oppressed | (adjective) burdened psychologically or mentally | Synonyms: laden |
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| oppressive | (adjective) marked by unjust severity or arbitrary behavior | Synonyms: tyrannical, tyrannous |
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| (adjective) weighing heavily on the senses or spirit | - |
| opprobrious | (adjective) (used of conduct or character) deserving or bringing disgrace or shame | Synonyms: black, disgraceful, ignominious, inglorious, shameful |
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| (adjective) expressing offensive reproach | Synonyms: abusive, scurrilous |