| irreclaimable | (adjective) insusceptible of reform | Synonyms: irredeemable, unredeemable, unreformable |
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| irreconcilable | (adjective) impossible to reconcile | Synonyms: unreconcilable |
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| irrecoverable | (adjective) incapable of being recovered or regained | Synonyms: unrecoverable |
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| irredeemable | (adjective) (of paper money) not convertible into coin at the pleasure of the holder | - |
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| (adjective) insusceptible of reform | Synonyms: irreclaimable, unredeemable, unreformable |
| irreducible | (adjective) incapable of being made smaller or simpler | - |
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| irrefutable | (adjective) impossible to deny or disprove | Synonyms: incontrovertible, positive |
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| irregular | (adjective) contrary to rule or accepted order or general practice | - |
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| (adjective) (of solids) not having clear dimensions that can be measured; volume must be determined with the principle of liquid displacement | - |
| (adjective) (used of the military) not belonging to or engaged in by regular army forces | - |
| (adjective) deviating from normal expectations; somewhat odd, strange, or abnormal | Synonyms: atypical |
| (adjective) failing to meet a standard of manufacture due to an imperfection | - |
| (adjective) lacking continuity or regularity | Synonyms: temporary |
| (adjective) not occurring at a regular rate or fixed intervals | Synonyms: unpredictable |
| (adjective) independent in behavior or thought | Synonyms: maverick, unorthodox |
| (adjective) (of a surface or shape); not level or flat or symmetrical | - |
| irrelevant | (adjective) having no bearing on or connection with the subject at issue | - |
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| irreligious | (adjective) hostile or indifferent to religion | - |
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| irremediable | (adjective) impossible to remedy or correct or redress | - |
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| irremovable | (adjective) incapable of being removed or away or dismiss | - |
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| irreparable | (adjective) impossible to repair, rectify, or amend | - |
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| irreplaceable | (adjective) impossible to replace | Synonyms: unreplaceable |
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| irrepressible | (adjective) impossible to repress or control | Synonyms: uncontrollable |
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| irreproachable | (adjective) free of guilt; not subject to blame | Synonyms: blameless, inculpable, unimpeachable |
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| irreproducible | (adjective) impossible to reproduce or duplicate | Synonyms: unreproducible |
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| irresistible | (adjective) impossible to resist; overpowering | Synonyms: resistless |
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| (adjective) overpoweringly attractive | - |
| irresolute | (adjective) uncertain how to act or proceed | - |
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| irresponsible | (adjective) showing lack of care for consequences | - |
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| irretrievable | (adjective) impossible to recover or recoup or overcome | Synonyms: unretrievable |
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| irreverent | (adjective) showing lack of due respect or veneration | - |
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| (adjective) not revering god | Synonyms: godless |
| (adjective) characterized by a lightly pert and exuberant quality | Synonyms: impertinent, pert, saucy |
| irreversible | (adjective) incapable of being reversed | - |
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| irrevocable | (adjective) incapable of being retracted or revoked | Synonyms: irrevokable |
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| irrevokable | (adjective) incapable of being retracted or revoked | Synonyms: irrevocable |
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