| disabled | (adjective) the total or partial absence of a person's bodily or mental functions, including the absence of a part of a person's body | Synonyms: handicapped |
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| disabling | (adjective) depriving of legal right; rendering legally disqualified | Synonyms: disqualifying |
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| (adjective) that cripples or disables or incapacitates | Synonyms: crippling, incapacitating |
| disabused | (adjective) freed of a mistaken or misguided notion | Synonyms: undeceived |
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| disadvantaged | (adjective) marked by deprivation especially of the necessities of life or healthful environmental influences | Synonyms: deprived |
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| disadvantageous | (adjective) involving or creating circumstances detrimental to success or effectiveness | Synonyms: unfavorable, unfavourable |
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| disaffected | (adjective) discontented as toward authority | Synonyms: ill-affected, malcontent, rebellious |
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| disagreeable | (adjective) not to your liking | - |
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| (adjective) unpleasant to interact with | - |
| (adjective) not agreeing with your tastes or expectations | Synonyms: unsympathetic |
| disappointed | (adjective) disappointingly unsuccessful | Synonyms: defeated, discomfited, foiled, frustrated, thwarted |
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| disappointing | (adjective) not up to expectations | Synonyms: dissatisfactory, unsatisfying |
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| disapproving | (adjective) expressing or manifesting disapproval | - |
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| disarming | (adjective) capable of allaying hostility | - |
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| disarranged | (adjective) having the arrangement disturbed; not in order | - |
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| disarrayed | (adjective) in disarray | - |
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| disastrous | (adjective) (of events) having extremely unfortunate or dire consequences; bringing ruin | Synonyms: black, calamitous, fatal, fateful |
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| disavowable | (adjective) capable of being disavowed | - |
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