| cupric | (adjective) of or containing divalent copper | Synonyms: cuprous |
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| cuprous | (adjective) of or containing divalent copper | Synonyms: cupric |
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| supranational | (adjective) transcending established national boundaries or spheres of interest | - |
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| supranormal | (adjective) beyond the range of the normal or scientifically explainable | Synonyms: supernormal |
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| supraocular | (adjective) located or occurring above the eye socket | Synonyms: supraorbital |
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| supraorbital | (adjective) located or occurring above the eye socket | Synonyms: supraocular |
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| suprasegmental | (adjective) pertaining to a feature of speech that extends over more than a single speech sound | - |
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| supreme | (adjective) greatest in status or authority or power | Synonyms: sovereign |
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| (adjective) greatest or maximal in degree; extreme | Synonyms: sublime |
| (adjective) highest in excellence or achievement | - |
| (adjective) final or last in your life or progress | - |
| upraised | (adjective) held up in the air | Synonyms: lifted |
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| upright | (adjective) upright in position or posture | Synonyms: erect, vertical |
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| (adjective) of moral excellence | Synonyms: good, just |
| (adjective) in a vertical position; not sloping | Synonyms: unsloped |
| uproarious | (adjective) marked by or causing boisterous merriment or convulsive laughter | Synonyms: hilarious, screaming |
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| (adjective) uncontrollably noisy | Synonyms: rackety, rip-roaring |