| upscale | (adjective) appropriate for people with good incomes | - |
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| upset | (adjective) thrown into a state of disarray or confusion | Synonyms: broken, confused, disordered |
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| (adjective) mildly physically distressed | - |
| (adjective) afflicted with or marked by anxious uneasiness or trouble or grief | Synonyms: disquieted, distressed, disturbed, worried |
| (adjective) having been turned so that the bottom is no longer the bottom | Synonyms: overturned, upturned |
| (adjective) used of an unexpected defeat of a team favored to win | - |
| (noun) an improbable and unexpected victory | Synonyms: overturn |
| (noun) the act of disturbing the mind or body | Synonyms: derangement, overthrow |
| (noun) the act of upsetting something | Synonyms: overturn, turnover |
| (noun) a tool used to thicken or spread metal (the end of a bar or a rivet etc.) by forging or hammering or swaging | Synonyms: swage |
| (noun) an unhappy and worried mental state | Synonyms: disturbance, perturbation |
| (noun) a physical condition in which there is a disturbance of normal functioning | Synonyms: disorder |
| (verb) disturb the balance or stability of | - |
| (verb) defeat suddenly and unexpectedly | - |
| (verb) form metals with a swage | Synonyms: swage |
| (verb) move deeply | Synonyms: disturb, trouble |
| (verb) cause to lose one's composure | Synonyms: discomfit, discompose, disconcert, untune |
| (verb) cause to overturn from an upright or normal position | Synonyms: bowl over, knock over, overturn, tip over, tump over, turn over |
| upsetter | (noun) an unexpected winner; someone who defeats the favorite competitor | - |
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| upsetting | (adjective) causing an emotional disturbance | Synonyms: disconcerting |
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| upshot | (noun) a phenomenon that follows and is caused by some previous phenomenon | Synonyms: consequence, effect, event, issue, outcome, result |
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| upside | (noun) the highest or uppermost side of anything | Synonyms: top, top side, upper side |
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| upsilon | (noun) the 20th letter of the Greek alphabet | - |
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| upstage | (adjective) of the back half of a stage | - |
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| (adjective) remote in manner | Synonyms: aloof, distant |
| (noun) the rear part of the stage | - |
| (adverb) at or toward the rear of the stage | - |
| (verb) steal the show, draw attention to oneself away from someone else | - |
| (verb) move upstage, forcing the other actors to turn away from the audience | - |
| (verb) treat snobbishly, put in one's place | - |
| upstager | (noun) a selfish actor who upstages the other actors | - |
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| upstair | (adjective) on or of upper floors of a building | Synonyms: upstairs |
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| upstairs | (adjective) on or of upper floors of a building | Synonyms: upstair |
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| (noun) the part of a building above the ground floor | - |
| (adverb) on a floor above | Synonyms: on a higher floor, up the stairs |
| (adverb) with respect to the mind | - |
| upstanding | (adjective) meriting respect or esteem | Synonyms: solid |
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| upstart | (adjective) characteristic of someone who has risen economically or socially but lacks the social skills appropriate for this new position | Synonyms: nouveau-riche, parvenu, parvenue |
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| (noun) a gymnastic exercise performed starting from a position with the legs over the upper body and moving to an erect position by arching the back and swinging the legs out and down while forcing the chest upright | Synonyms: kip |
| (noun) a person who has suddenly risen to a higher economic status but has not gained social acceptance of others in that class | Synonyms: arriviste, nouveau-riche, parvenu |
| (noun) an arrogant or presumptuous person | - |
| upstate | (adverb) in or toward the northern parts of a state | - |
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| upstream | (adjective) in the direction against a stream's current | - |
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| (adverb) toward the source or against the current | Synonyms: upriver |
| upstroke | (noun) a stroke normally made in an upward direction | - |
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| upsurge | (noun) a sudden or abrupt strong increase | Synonyms: surge |
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| (noun) a sudden forceful flow | Synonyms: rush, spate, surge |