| acrosome | (noun) a process at the anterior end of a sperm cell that produces enzymes to facilitate penetration of the egg | - |
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| adventuresome | (adjective) willing to undertake or seeking out new and daring enterprises | Synonyms: adventurous |
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| autosome | (noun) any chromosome that is not a sex chromosome; appear in pairs in body cells but as single chromosomes in spermatozoa | Synonyms: somatic chromosome |
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| awesome | (adjective) inspiring awe or admiration or wonder | Synonyms: amazing, awe-inspiring, awful, awing |
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| blithesome | (adjective) carefree and happy and lighthearted | Synonyms: blithe, light-hearted, lighthearted, lightsome |
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| bothersome | (adjective) causing irritation or annoyance | Synonyms: annoying, galling, irritating, nettlesome, pesky, pestering, pestiferous, plaguey, plaguy, teasing, vexatious, vexing |
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| bunglesome | (adjective) difficult to handle or manage especially because of shape | Synonyms: awkward, clumsy, ungainly |
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| burdensome | (adjective) not easily borne; wearing | Synonyms: onerous, taxing |
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| centrosome | (noun) small region of cytoplasm adjacent to the nucleus; contains the centrioles and serves to organize the microtubules | Synonyms: central body |
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| chondriosome | (noun) an organelle containing enzymes responsible for producing energy | Synonyms: mitochondrion |
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| chromosome | (noun) a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order | - |
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| cuddlesome | (adjective) inviting cuddling or hugging | Synonyms: cuddly |
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| cumbersome | (adjective) not elegant or graceful in expression | Synonyms: awkward, clumsy, ill-chosen, inapt, inept |
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| (adjective) difficult to handle or use especially because of size or weight | Synonyms: cumbrous |
| dictyosome | (noun) a netlike structure in the cytoplasm of animal cells (especially in those cells that produce secretions) | Synonyms: Golgi apparatus, Golgi body, Golgi complex |
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| eightsome | (noun) a Scottish reel for eight dancers | - |
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| (noun) eight people considered as a unit | Synonyms: octet, octette |
| episome | (noun) DNA that is not incorporated into the genome but is replicated together with the genome (especially in bacterial cells) | - |
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| fearsome | (adjective) causing fear or dread or terror | Synonyms: awful, dire, direful, dread, dreaded, dreadful, fearful, frightening, horrendous, horrific, terrible |
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| fivesome | (noun) five people considered as a unit | Synonyms: quintet, quintette |
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| (noun) the cardinal number that is the sum of four and one | Synonyms: 5, cinque, fin, five, Little Phoebe, pentad, Phoebe, quint, quintet, quintuplet, V |
| flavorsome | (adjective) full of flavor | Synonyms: flavorful, flavorous, flavourful, flavourous, flavoursome, sapid, saporous |
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| flavoursome | (adjective) full of flavor | Synonyms: flavorful, flavorous, flavorsome, flavourful, flavourous, sapid, saporous |
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| foursome | (noun) four people considered as a unit | Synonyms: quartet, quartette |
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| (noun) the cardinal number that is the sum of three and one | Synonyms: 4, four, IV, Little Joe, quadruplet, quartet, quatern, quaternary, quaternion, quaternity, tetrad |
| frolicsome | (adjective) given to merry frolicking | Synonyms: coltish, frolicky, rollicking, sportive |
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| fulsome | (adjective) unpleasantly and excessively suave or ingratiating in manner or speech | Synonyms: buttery, oily, oleaginous, smarmy, soapy, unctuous |
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| gladsome | (adjective) experiencing or expressing gladness or joy | - |
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| gruesome | (adjective) shockingly repellent; inspiring horror | Synonyms: ghastly, grim, grisly, macabre, sick |
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| handsome | (adjective) pleasing in appearance especially by reason of conformity to ideals of form and proportion | Synonyms: better-looking, fine-looking, good-looking, on fleek, well-favored, well-favoured |
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| (adjective) given or giving freely | Synonyms: big, bighearted, bounteous, bountiful, freehanded, giving, liberal, openhanded |
| irksome | (adjective) so lacking in interest as to cause mental weariness | Synonyms: boring, deadening, dull, ho-hum, slow, tedious, tiresome, wearisome |
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| lightsome | (adjective) carefree and happy and lighthearted | Synonyms: blithe, blithesome, light-hearted, lighthearted |
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| (adjective) moving easily and quickly; nimble | Synonyms: light, tripping |
| liposome | (noun) an artificially made microscopic vesicle into which nucleic acids can be packaged; used in molecular biology as a transducing vector | - |
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| lissome | (adjective) gracefully thin and bending and moving with ease | Synonyms: lissom, lithe, lithesome, sinuous, supple |
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| lithesome | (adjective) gracefully thin and bending and moving with ease | Synonyms: lissom, lissome, lithe, sinuous, supple |
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| loathsome | (adjective) highly offensive; arousing aversion or disgust | Synonyms: disgustful, disgusting, distasteful, foul, loathly, repellant, repellent, repelling, revolting, skanky, wicked, yucky |
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| (adjective) causing or able to cause nausea | Synonyms: nauseating, nauseous, noisome, offensive, queasy, sickening, vile |
| lonesome | (adjective) marked by dejection from being alone | Synonyms: lonely |
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| (adjective) being the only one; single and isolated from others | Synonyms: lone, only, sole, solitary |
| lovesome | (adjective) having or displaying warmth or affection | Synonyms: affectionate, fond, tender |
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| lysosome | (noun) an organelle found in the cytoplasm of most cells (especially in leukocytes and liver and kidney cells) | - |
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| meddlesome | (adjective) intrusive in a meddling or offensive manner | Synonyms: busy, busybodied, interfering, meddling, officious |
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| mettlesome | (adjective) willing to face danger | Synonyms: game, gamey, gamy, gritty, spirited, spunky |
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| (adjective) having a proud and unbroken spirit | - |
| microsome | (noun) a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA | - |
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| nettlesome | (adjective) causing irritation or annoyance | Synonyms: annoying, bothersome, galling, irritating, pesky, pestering, pestiferous, plaguey, plaguy, teasing, vexatious, vexing |
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| (adjective) easily irritated or annoyed | Synonyms: cranky, fractious, irritable, peckish, peevish, pettish, petulant, scratchy, techy, testy, tetchy |
| noisome | (adjective) offensively malodorous | Synonyms: fetid, foetid, foul-smelling, foul, funky, ill-scented, smelly, stinking |
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| (adjective) causing or able to cause nausea | Synonyms: loathsome, nauseating, nauseous, offensive, queasy, sickening, vile |
| proteosome | (noun) a form of vaccine that can be administered by an inhaler | Synonyms: proteosome vaccine |
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| quarrelsome | (adjective) given to quarreling | - |
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| ribosome | (noun) an organelle in the cytoplasm of a living cell; they attach to mRNA and move down it one codon at a time and then stop until tRNA brings the required amino acid; when it reaches a stop codon it falls apart and releases the completed protein molecule for use by the cell | - |
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| sarcosome | (noun) a large mitochondrion in a striated muscle fiber | - |
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| schistosome | (noun) flatworms parasitic in the blood vessels of mammals | Synonyms: blood fluke |
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| sevensome | (noun) seven people considered as a unit | Synonyms: septet, septette |
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| sixsome | (noun) six people considered as a unit | Synonyms: sextet, sextette |
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| some | (adjective) (quantifier) used with either mass nouns or plural count nouns to indicate an unspecified number or quantity | - |
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| (adjective) remarkable | - |
| (adjective) relatively many but unspecified in number | - |
| (adverb) (of quantities) imprecise but fairly close to correct | Synonyms: about, approximately, around, close to, just about, more or less, or so, roughly |
| threesome | (noun) three people considered as a unit | Synonyms: triad, trinity, trio |
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| (noun) the cardinal number that is the sum of one and one and one | Synonyms: 3, deuce-ace, III, leash, tercet, ternary, ternion, terzetto, three, tierce, trey, triad, trine, trinity, trio, triplet, troika |
| tiresome | (adjective) so lacking in interest as to cause mental weariness | Synonyms: boring, deadening, dull, ho-hum, irksome, slow, tedious, wearisome |
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| toilsome | (adjective) characterized by effort to the point of exhaustion; especially physical effort | Synonyms: arduous, backbreaking, grueling, gruelling, hard, heavy, laborious, operose, punishing |
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| toothsome | (adjective) acceptable to the taste or mind | Synonyms: palatable |
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| (adjective) having strong sexual appeal | Synonyms: juicy, luscious, lush, red-hot, voluptuous |
| (adjective) extremely pleasing to the sense of taste | Synonyms: delectable, delicious, luscious, pleasant-tasting, scrumptious, yummy |
| torturesome | (adjective) extremely painful | Synonyms: agonising, agonizing, excruciating, harrowing, torturing, torturous |
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| troublesome | (adjective) causing difficulty or annoyance | - |
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| twosome | (noun) a pair who associate with one another | Synonyms: couple, duet, duo |
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| (noun) two items of the same kind | Synonyms: brace, couple, couplet, distich, duad, duet, duo, dyad, pair, span, twain, yoke |
| unwholesome | (adjective) detrimental to physical or moral well-being | - |
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| venturesome | (adjective) disposed to venture or take risks | Synonyms: audacious, daring, venturous |
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| wearisome | (adjective) so lacking in interest as to cause mental weariness | Synonyms: boring, deadening, dull, ho-hum, irksome, slow, tedious, tiresome |
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| wholesome | (adjective) conducive to or characteristic of physical or moral well-being | - |
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| (adjective) sound or exhibiting soundness in body or mind | - |
| winsome | (adjective) charming in a childlike or naive way | - |
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| worrisome | (adjective) not reassuring; tending to cause anxiety | Synonyms: unreassuring |
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| (adjective) causing distress or worry or anxiety | Synonyms: distressful, distressing, disturbing, perturbing, troubling, worrying |