| zaftig | (adjective) (of a female body) healthily plump and vigorous | Synonyms: buxom, zoftig |
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| zany | (adjective) ludicrous, foolish | Synonyms: goofy, silly, wacky, whacky |
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| (adjective) like a clown | Synonyms: buffoonish, clownish, clownlike |
| zealous | (adjective) marked by active interest and enthusiasm | Synonyms: avid |
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| zenithal | (adjective) relating to or located at or near the zenith | - |
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| zero | (adjective) of or relating to the null set (a set with no members) | - |
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| (adjective) indicating the absence of any or all units under consideration | Synonyms: 0 |
| (adjective) having no measurable or otherwise determinable value | - |
| (adjective) indicating an initial point or origin | - |
| zeroth | (adjective) preceding even the first | - |
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| zestful | (adjective) marked by spirited enjoyment | Synonyms: barmy, yeasty, zesty |
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| zesty | (adjective) marked by spirited enjoyment | Synonyms: barmy, yeasty, zestful |
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| (adjective) having an agreeably pungent taste | Synonyms: piquant, savory, savoury |
| zigzag | (adjective) having short sharp turns or angles | Synonyms: zig-zag |
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| zillion | (adjective) very large indeterminate number | - |
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| zippy | (adjective) quick and energetic | Synonyms: alert, brisk, lively, merry, rattling, snappy, spanking |
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| (adjective) marked by lively action | Synonyms: bouncing, bouncy, peppy, spirited |
| zodiacal | (adjective) relating to or included in the zodiac | - |
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| zoftig | (adjective) (of a female body) healthily plump and vigorous | Synonyms: buxom, zaftig |
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| zoic | (adjective) pertaining to animals or animal life or action | - |
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| zonal | (adjective) associated with or divided into zones | - |
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| (adjective) relating to or of the nature of a zone | Synonyms: zonary |
| zonary | (adjective) relating to or of the nature of a zone | Synonyms: zonal |
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| zoological | (adjective) of or relating to animals or animal groups | - |
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| (adjective) concerning the study of animals and their classification and properties | - |
| zoonotic | (adjective) of or relating to or constituting zoonosis | - |
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| zoophagous | (adjective) (of animals) carnivorous | Synonyms: flesh-eating, meat-eating |
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| zygodactyl | (adjective) (of bird feet) having the first and fourth toes directed backward the second and third forward | - |
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| zygomatic | (adjective) of or relating to the cheek region of the face | - |
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| zygomorphic | (adjective) capable of division into symmetrical halves by only one longitudinal plane passing through the axis | Synonyms: bilaterally symmetrical, zygomorphous |
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| zygomorphous | (adjective) capable of division into symmetrical halves by only one longitudinal plane passing through the axis | Synonyms: bilaterally symmetrical, zygomorphic |
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| zygotic | (adjective) of or relating to a zygote | - |
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| zymoid | (adjective) resembling an enzyme | - |
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| zymolytic | (adjective) of or relating to or causing fermentation | Synonyms: zymotic |
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| zymotic | (adjective) relating to or caused by infection | - |
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| (adjective) of or relating to or causing fermentation | Synonyms: zymolytic |