| poignant | (adjective) arousing affect | Synonyms: affecting, touching |
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| (adjective) keenly distressing to the mind or feelings | - |
| poikilothermic | (adjective) of animals except birds and mammals; having body temperature that varies with the environment | Synonyms: ectothermic, heterothermic, poikilothermous |
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| poikilothermous | (adjective) of animals except birds and mammals; having body temperature that varies with the environment | Synonyms: ectothermic, heterothermic, poikilothermic |
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| pointed | (adjective) having a point | - |
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| (adjective) direct and obvious in meaning or reference; often unpleasant | - |
| pointillist | (adjective) of or relating to pointillism | Synonyms: pointillistic |
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| pointillistic | (adjective) of or relating to pointillism | Synonyms: pointillist |
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| pointless | (adjective) not having a point especially a sharp point | Synonyms: unpointed |
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| (adjective) having no points scores | Synonyms: goalless, hitless, scoreless |
| (adjective) serving no useful purpose; having no excuse for being | Synonyms: otiose, purposeless, senseless, superfluous, wasted |
| poised | (adjective) marked by balance or equilibrium and readiness for action | - |
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| (adjective) in full control of your faculties | Synonyms: collected, equanimous, self-collected, self-contained, self-possessed |
| poisonous | (adjective) not safe to eat | - |
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| (adjective) marked by deep ill will; deliberately harmful | Synonyms: venomous, vicious |
| (adjective) having the qualities or effects of a poison | Synonyms: toxicant |